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The promoters contain binding sites for Nrf2, Ap-1, Ap-2, and NFκB transcription factors, and induction of GGT under conditions of redox stress has been demonstrated in several species (Reuter et al., 2009, Joyce-Brady et al., 2001, DeNicola et al., 2011, Hanigan, 2014)

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Researchers use this compound to observe how molecules respond under different test conditions within non-clinical research models