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Our review of the clinical evidence points toward 100-200mg as the optimal dose range, with doses much lower or much higher than that exhibiting weaker effects along something called a U-shaped curve.65 At 200mg, CoQ10 has been shown, among other things, to:66 67 68 69 Lower blood pressure Improve HDL cholesterol Regulate blood sugar Reduce statin-induced muscle pain Improve sperm characteristics We have not seen sufficient evidence that CoQ10 can reliably do any of these things at just 60mg