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[DOI] [PubMed] [Google Scholar] 72.Issac P.K., Karan R., Guru A., Pachaiappan R., Arasu M.V., Al-Dhabi N.A., Choi K.C., Harikrishnan R., Raj J.A

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Receptor Pathway Interaction Research The combination is used as a dual-pathway pharmacological tool to study how GHRH-R and GHSR-1a signalling interact at the pituitary level — examining signal transduction crosstalk, receptor co-activation dynamics, and how simultaneous activation of cAMP-PKA (GHRH-R) and calcium/PKC (GHSR-1a) intracellular pathways produces synergistic GH secretion in pituitary somatotroph models