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Recent epidemiological data have documented that the prevalence of COPD among adults aged 40 years and older ranges from 9% to 10% ( In addition to its direct harms to individual health, COPD imposes a substantial economic burden on families, healthcare systems, and society, driven by high medical expenditures and lost productivity ( 2 Risk factors for COPD Tobacco smoking stands as the paramount risk factor precipitating COPD