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RNS are primarily generated by the enzymatic activity of inducible nitric oxide synthase (iNOS), which is substantially upregulated in active MS lesions within macrophages, microglia, and astrocytes ( 2 •- to form ONOO − , a highly reactive oxidant that promotes protein nitration, lipid peroxidation, mitochondrial dysfunction, and axonal damage (Ohl et al., 2016)

referral: General Health

Amount:20mg

PMCID: PMC8389000.