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doi: 10.1067/mpd.2000.102940, PMID: [DOI] [PubMed] [Google Scholar] 40.Thornalley PJ

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After intraperitoneal injection into syngeneic mice, the CII-specific autoantibodies (activated IgG) induce synovial inflammation and even erosive arthritis by entering articular cartilage [79,93,95,96]