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These findings were supported by the relaxation of large vessels (ex vivo), mainly by acting on vascular endothelial cells but also on vascular smooth muscle cells, increasing NO production and migration of endothelial cells, activating the signal pathways of Src, Cav-1, and eNOS, and reducing proteinβprotein interaction between eNOS and Cav-1 [121,122]
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These properties make L-Glutathione important in laboratory models focused on oxidation-reduction balance, cellular stress responses and intracellular protective pathways
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