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Further insights regarding cytokine receptor recognition by JAKs emerged when the crystal structure of JAK1 bound to peptides derived from the IL-10 receptor (IL10RA) and interferon lambda receptor (IFNLR1) was solved (73)

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Favorece la comunicación celular en la reparación tisular y se ha relacionado con la modulación del óxido nítrico y la mejora de la vascularización en modelos de lesión