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It Might Be a Vitamin B12 Deficiency Overview of vitamin b12 deficiency anaemia : Vitamin B12 or B9 (commonly called folate) deficiency anaemia occurs when a lack of vitamin B12 or folate causes the body to produce abnormally large red blood cells that cannot function properly

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In people who are deficient, on the other hand, restoring B12 can meaningfully improve energy and how they feel day to day (a clinical review of B12, chronic fatigue, and injection treatment, published in Lakartidningen in 1999)