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4 to 5 wild-type or XpdTTD/TTD mice treated on day 0, 2 and 4 with 5 mg/kg FOXO4-DRI by intravenous injection, with a blood sample taken 28 days after the first injection, and for the chemotoxicity arm, a single dose of doxorubicin at 10 mg/kg i.p
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