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Given the impact of MTHFR polymorphisms on methylfolate production, nuclear methylation, and the production of monoamines, there has been considerable research examining the association between MTHFR genetic variations and psychiatric disease states including unipolar depression, bipolar depression, schizophrenia, and more

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Cagrilintide monotherapy produced 11.8% weight loss at 68 weeks in a dedicated Phase 3 trial, compared to 2.3% for placebo

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