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Why cysteine is the rate-limiting factor: The intracellular concentration of cysteine sits close to the Km value of GCL (0.1 to 0.3 mM), meaning the enzyme is operating near its saturation point under normal conditions

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However, due to emerging troubling side effects ( 20 sudden deaths, 12 strokes, many other cardio-related injuries, and addiction), Adderall was for a time banned in Canada and elsewhere

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